Genetic Breakdown In Fanconi Anemia May Have Link To HPV-associated Cancer

Thursday, December 4, 2008 - 17:43 in Biology & Nature

A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus, according to a new study. Researchers report breakdown of a cell signaling pathway for the FA gene complex triggers cellular abnormalities, when then are made worse by HPV cancer genes in skin cells.

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