Estrogen And Progesterone Receptor Isoforms Expression In Stomach Of Mongolian Gerbils
Friday, October 31, 2008 - 13:08
in Health & Medicine
Gerbils were treated with estradiol and E2+ progesterone. Stomach proteins were immunoblotted for Estrogen-alpha, ER-beta, progesterone receptor-A, PR-B. ER-alpha, PR-A and PR-B were detected. PR isoforms were not regulated by hormones. E2 down-regulated ER-alpha in corpus. This suggests that E2 and P4 actions in stomach are mediated by their nuclear receptors.
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