Determining The Structure Of Nuclear Receptor Has Implications For A Host Of Diseases

Thursday, September 18, 2008 - 22:14 in Biology & Nature

Researchers have determined the molecular structure of a nuclear receptor, which regulates the expression of specific genes within cells, that may serve as a drug target for diseases related to heart and blood vessel development, human embryonic development and female infertility. Researchers also found that the receptor, named COUP-TFII, is activated by retinoic acid, a form of Vitamin A.

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