Why Gene Therapy Caused Leukemia In Some 'Boy In The Bubble Syndrome' Patients

Saturday, August 9, 2008 - 22:28 in Health & Medicine

Severe combined immunodeficiency (SCID), sometimes called 'Boy in the bubble syndrome', is a genetic disorder in which the patient lacks most types of immune cell. Almost 10 years ago, two independent groups used gene therapy to treat a few infants with the most common form of SCID, SCID-X1, which is caused by mutations in the IL2RG gene.

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