Researchers Halt Spread Of HIV With RNAi In Animal Model

Thursday, August 7, 2008 - 18:21 in Biology & Nature

Using a novel method to deliver small molecules called siRNAs into T cells, researchers dramatically suppressed HIV in the first-ever animal model that mirrors progression of the disease in humans. The siRNAs knocked down three key genes and kept the infection from spreading in mice containing human immune cells infected with the virus.

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