Predicting Acute GVHD By Gene Expression Could Improve Liver Stem Cell Transplant Outcomes

Monday, July 21, 2008 - 00:21 in Health & Medicine

Acute graft-versus-host disease occurs when an immune response is elicited by the grafted cells against a recipient, resulting in tissue damage for the treated individual. There are no definitive markers for predicting the development or progression of GVHD following the transplant of allogenic stem cells as therapy for liver cancer. This study offers a preliminary "molecular signature" for the development of acute GVHD based on altered gene expression.

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