Normal-looking Sperm May Have Serious Damage; Scientists Urge More Care In Selection

Intracytoplasmic sperm injection (ICSI) where a single sperm is injected into an egg to fertilize it, is increasingly used to help infertile men father children. Although the sperm chosen for the procedure may appear quite normal, researchers in the US have found that many of them in fact have DNA damage, which can decrease the chances of pregnancy and increase chances of later miscarriage if pregnancy does occur. In infertile men, between 20 and 66% of normal-looking sperm had DNA damage.

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