DNA Knot Keeps Viral Genes Tightly Corked Inside Shell, Scientists Discover

A novel twist of DNA may keep viral genes tightly wound within a capsule, waiting for ejection into a host, a high-resolution analysis of its structure has revealed. Using electron microscopy and three-dimensional computer reconstruction, biologists and chemists have produced the most detailed image yet of the protein envelope of an asymmetrical virus and the viral DNA packed within.

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