Infectious And Non-infectious Prions Have Clear Differences In Molecular Structures

Thursday, June 19, 2008 - 15:28 in Biology & Nature

Infectious proteins known as prions have been identified as the cause of “mad cow” disease (BSE). The culprits are “incorrectly folded” proteins that can “infect” healthy proteins. The molecular bases for such prion diseases are not yet fully understood. Why are some proteins infectious while others are not? Scientists examined two different forms of a prion-forming protein domain by means of NMR spectroscopy and found that the infectious and noninfectious forms differ markedly in their molecular structure.

Read the whole article on Science Daily

More from Science Daily

Latest Science Newsletter

Get the latest and most popular science news articles of the week in your Inbox! It's free!

Check out our next project, Biology.Net