Of 50,000 small molecules tested to fight cancer, 2 show promise

A class of compounds that interferes with cell signalling pathways may provide a new approach to cancer treatment, according to a study published online this week in the Proceedings of the National Academy of Sciences (PNAS) Early Edition. The compounds, called PITs (non-phosphoinositide PIP3 inhibitors), limited tumour growth in mice by inducing cell death...

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