Study explains some mysteries of neonatal seizures

Thursday, September 10, 2009 - 08:21 in Psychology & Sociology

A study led by MassGeneral Hospital for Children (MGHfC) investigators is providing new insight into the mechanism of neonatal seizures, which have features very different from seizures in older children and adults. In their report in the Sept. 10 issue of Neuron, the researchers describe finding how neurones in different parts of the brains of newborn mammals respond differently to the neurotransmitter GABA, an observation that may explain why seizure activity in the neonatal brain often does not produce visible convulsions and why the common antiseizure drug phenobarbital can exacerbate the invisible nature of neonatal seizures...

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