The protein CCKR2: A potential drug target for colorectal cancer?
Tuesday, August 4, 2009 - 06:28
in Health & Medicine
Colorectal cancer, the second most common cause of death from cancer in the United States, is associated with an abnormally high rate of increase in the number of cells lining the colon (colonic hyperproliferation). In mice, overexpression of the human protein progastrin has been shown to cause colonic hyperproliferation and promote colorectal cancer, but the molecular mechanisms underlying this have remained undetermined...