MGH study identifies first molecular steps to childhood leukaemia
Wednesday, July 15, 2009 - 23:21
in Health & Medicine
A Massachusetts General Hospital (MGH)-based research team has identified how a chromosomal abnormality known to be associated with acute lymphoblastic leukaemia (ALL) - the most common cancer in children - initiates the disease process. In the July issue of Cell Stem Cell, they describe how expression of this mutation in haematopoietic stem cells (HSCs), which usually occurs before birth, leads to the development of leukaemia many years later...