How to get obese mice moving - and cure their diabetes

Thursday, June 4, 2009 - 08:35 in Biology & Nature

Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic - not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control in those animals can be completely restored by returning leptin sensitivity to a single class of neurones in the brain, which account for only a small fraction of those that normally carry the hormone receptors...

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