Penn biologists discover how 'silent' mutations influence protein production

Friday, April 10, 2009 - 08:49 in Biology & Nature

Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. The new research, which involved creating hundreds of synthetic green-glowing genes, provides an explanation for how a cell 'knows' how much of each protein to make, providing just the right amount of protein to maintain homeostasis yet not too much to cause cell toxicity...

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