New pathway is a common thread in age-related neurodegenerative diseases

Monday, February 2, 2009 - 04:49 in Biology & Nature

How are neurodegenerative diseases such as Alzheimer's initiated, and why is age the major risk factor? A recent study of a protein called MOCA (Modifier of Cell Adhesion), carried out at the Salk Institute for Biological Studies, provides new clues to the answers of these fundamental questions. Under normal circumstances, MOCA is a key member of the squadron charged with keeping Alzheimer's disease at bay. A team of researchers led by Salk professor David Schubert, Ph.D., demonstrated what happens when MOCA goes on furlough...

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