Antibodies produced within joints in rheumatoid arthritis

Tuesday, January 13, 2009 - 11:14 in Health & Medicine

Antibodies produced within the joints themselves may be responsible for joint damage in rheumatoid arthritis, according to new research published in PLoS Medicine. Studying joint biopsies from people with rheumatoid arthritis, Costantino Pitzalis of Barts and the London School of Medicine and colleagues found that tiny structures in the joint lining mimic key functions of antibody-producing lymph nodes, and can support the production of specific antibodies that may play a role in joint destruction...

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