Pitt scientists find intrinsic changes in protein shape influence drug binding
Wednesday, August 19, 2009 - 12:15
in Biology & Nature
PITTSBURGH, Aug. 19 -- Computational biologists at the University of Pittsburgh School of Medicine have shown that proteins have an intrinsic ability to change shape, and this is required for their biological activity. This shape-changing also allows the small molecules that are attracted to a given protein to select the structure that permits the best binding.
Read the whole article on Science Blog
More from Science Blog
Related
- Pitt scientists find intrinsic changes in protein shape influence drug bindingWed, 19 Aug 2009, 13:18:40 EDT
- Shape of things to come: Structure of HIV coat could lead to new drugs, says Pitt teamThu, 12 Nov 2009, 12:46:06 EST
- Stressed proteins can cause blood clots for hoursTue, 5 Mar 2013, 16:34:43 EST
- Newly discovered regulatory mechanism essential for embryo development and may contribute to cancerThu, 28 Oct 2010, 16:36:54 EDT
- Computer-designed proteins programmed to disarm variety of flu viruses Sun, 3 Jun 2012, 0:33:06 EDT