Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols

COLD SPRING HARBOR, N.Y. (Wed., Aug. 5, 2009) -- Vectors derived from retroviruses are useful tools for long-term gene transfer because they allow stable integration of transgenes and propagation into daughter cells. Lentiviral vectors are preferred because they can transduce non-proliferating cellular targets. These vectors can be engineered to target specific tissues.

Read the whole article on Science Blog

More from Science Blog