Common insecticide used in homes associated with delayed mental development of young children
When the EPA phased out the widespread residential use of chlorpyrifos and other organophosphorus (OP) insecticides in 2000-2001 because of risks to child neurodevelopment, these compounds were largely replaced with pyrethroid insecticides. But the safety of these replacement insecticides remained unclear, as they had never been evaluated for long-term neurotoxic effects after low-level exposure. In the first study to examine the effects of these compounds on humans and the first evaluation of their potential toxicity to the developing fetal brain, scientists of the Columbia Center for Children's Environmental Health at Columbia University's Mailman School of Public Health found a significant association between piperonyl butoxide (PBO), a common additive in pyrethroid formulations, measured in personal air collected during the third trimester of pregnancy, and delayed mental development at 36 months. Findings from the study are online in the journal, Pediatrics.