Penn bioengineers show why lab-made stem cells might fail: Errors in DNA folding
Tuesday, May 10, 2016 - 16:10
in Biology & Nature
Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don't always correctly differentiate back into adult cells.