... describe how four different human tumor cells lines out of 16 tested were sensitive to the chemical ... , in cervical cancer cells and in one line of leukemia, tumor cells. Other cell lines were resistant, including ...
... of a tumor-promoting gene. One form of the gene, the isoform NSP5a3a, is highly expressed in some tumor cell lines and could be very useful as a tumor marker, Giordano said. A protein ...
... model. We chose adriamycin for this study because it is one of the most effective drugs against brain tumor cell lines in the laboratory but it has very little effect ...
... relies on xenografts: Human tumor tissue or cancer cell lines are transplanted in immuno-compromised ... -Morvinski. Most xenograft models for brain tumors using tumor cell lines require at least 10 ...
... gene. At the cellular level, FHL1, FHL2, and FHL3 inhibited the growth of a human tumor cell line both in vitro and when transplanted into mice ... -and-a-half LIM family members suppress tumor cell growth through a TGF-beta ...
... in patients. While the study was restricted to tumor cell lines, rather than using animal models or human ... . Two earlier studies on different tumor cell lines – one prepared from a multiple myeloma and the other from a nasopharyngeal ...
... one specific cellular compartment in which Hsp90 is active in tumor cells, mitochondria. Importantly, treatment with these drugs ... death in mice transplanted with human tumor cell lines. The authors therefore conclude that combinatorial ...
... tumors respond to dietary restriction during their development. Studying human cancer cell lines ... no such mutations. Using a DR-resistant tumor cell line in which the PTEN gene could be switched on or off ...
... 50 specific microRNAs were expressed at higher or lower levels in head and neck tumor cell lines compared with normal cells. In this study, the Einstein researchers, for the first time, have linked ...
... activity to mutated p53. The effect of this is that tumor cell lines with mutant p53 became more sensitive ... pathways have been restored in the mutant p53-expressing tumor cells. This novel finding suggests that the PEITC ...
... . They also found AZ23 to be more effective in human AML cell lines that expressed higher levels of TRKA. This pre ... cancer cell production is one way to do this." In pre-clinical tests on solid tumor cell lines, AZ23 was found effective against ...
... into a cancer cell could re-establish a more normally functioning cell. Killary noted that when tumor cell lines containing a DEAR1 ...
... 80 percent of all solid tumors originate in the epithelial cells, which line an organ or its cavities and are generally ... characterized for metastatic potential. All tumor cell lines were profiled for gene expression. "The thing that popped ...
... to migrate. The research offers new insights into how tumor cells invade their surrounding environment and may eventually ... our investigations have utilized melanoma and breast tumor cell lines, microvesicle release has been observed in a variety ...
... lower levels of DC-SCRIPT mRNA than normal breast tissue and that breast tumor cell lines do not express it. "On the basis of these findings ...
