... the prime challenge in anti-cancer therapy: improving treatments' ability to specifically and effectively target cancer cells. Using this new approach, scientists should be able to insert "self- ...
... high acidity.
DELIVERY METHOD
In addition to targeting cancerous tumors, the couple has discovered a novel ... million National Institutes of Heath/National Cancer Institute grant Jason S. Lewis, chief ...
... cell membrane into the cell," Hung said.
A "terrific target"
Cancer cells have a high metabolic rate ... glucose levels in two sets of prostate cancer cells - one treated by a tyrosine kinase inhibitor ...
... 100 genes that work downstream of known cancer-causing mutations, providing a host of new ... stem cells,” he said.
Targeted cancer therapy – such as the drug Gleevec that works for patients with certain ...
... reasons, tumor suppressors like DLC1 are not amenable to direct therapeutic targeting. But we may be able to readily target cancer-promoting molecules like RhoA that are 'downstream' in the signaling ...
... treat—or even prevent—many viral cancers by targeting cancer cells expressing viral antigens ... under development for thirty years. However, the targets of RIT therapy to date have included only "self" ...
... normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing ... treatments, the team said. At present, no drugs target Myc. Understanding the Myc threshold will make ...
... and Lapatanib, are so effective in breast cancer is that they target the cancer stem cell population. This finding ... HER2 gene had four to five times more cancer stem cells, compared to HER2-negative ...
... reveals scientists a promising novel anti-cancer drug target. Cancer cells have multiple ways ... lipid second messenger can act as a drug target: it is a totally new mechanism of action and constitutes ...
... safer and more effective way of targeting cancer-causing genes in cancer cells without harming ... genes, which then lowers the abnormal levels of the cancer causing proteins in cells," explained Robertson ...
... Health Research Institute (OHRI) –report a significant breakthrough in the use of viruses to target and destroy cancer cells, a field known as oncolytic virotherapy. Their results were published in ...
... they find may be cost-prohibitive.
Personalized medicine and targeted cancer therapies are being offered at many academic medical ...
... governing stem cell expansion in breast cancer (called Notch activity), and finds that therapy ... cancer stem cells. By specifically targeting cancer stem cells we hope to reduce recurrence and improve ...
... D., a Mayo Clinic cancer researcher. "Most cancer therapies target cancer growth, but miss ... uniquely devoted to understanding, and then halting, cancer metastasis. Dr. Anastasiadis and his collaborators ...
... effectively treat K-Ras-mutated cancers would be a huge advance in solid tumor ... associated tumors will become resistant to combination therapy, a problem that has plagued other targeted cancer therapies ...
