A new method now enables researchers to study hundreds of cell-surface proteins simultaneously. The results obtained could help to develop more accurate diagnostic tests and more specific therapies in ...
... ve reduced the expression of CCR5 surface proteins on T cells, which is necessary for the AIDS virus ... process a new mutation arises in the CCR5 protein, rendering it non-functional. Without a functional ...
... inside the female reproductive tract. The changes sperm undergo during this process include redistribution of surface proteins, loss of sperm membrane lipids and increased sperm movement. A family of ...
... carcinoma in situ (DCIS). However, that same protein is overexpressed in only about 25 percent of invasive breast ... together in zipper-like fashion by the cell surface protein E-cadherin, a trait known ...
... role in allowing the trypanosome to avoid the immune system of the host. The FP permits the trypanosomes’ surface proteins (the structures seen by the immune system) to be changed, so that the bug can ...
... an EMT, his tests did highlight surface proteins that are key markers for stem cells.
... -like in appearance and demonstrated stem-cell surface markers. The cells also displayed an increased ability to ...
... looked to see if EhROM1 follows lectin and sure enough found that EhROM1 clusters at the cap—the cluster of surface proteins waiting to be shed.
"We're excited to see if EhROM1 plays a specific role ...
... . histolytica trophozoites concentrate immune system-eliciting surface proteins towards the rear of the cell and then expel them. Dr. Urban's team discovered that EhROM1 processes surface lectin ...
... . They used a process called immunohistochemistry which involves using antibodies which bind to specific surface proteins, enabling the virus particles to be located. There was no evidence of virus ...
... Saphire. "This structure now provides templates by which researchers studying other viruses could try to understand how their virus's surface protein is assembled and neutralized by an antibody."
... proteins." The team experimentally decreased levels of one of those — a sticky surface protein called DE-cadherin that likely allows stem cells to latch on to the support hub — but ...
... a single amino acid residue (Leu226) at the receptor-binding site (RBS) of the hemagglutinin (HA) surface protein plays a major role in the ability of these viruses to transmit. They also found that ...
... stem cells also depend on integrins, cell surface proteins that link molecules in the extracellular matrix ... Integrins hook onto an extracellular matrix protein called laminin A. FSCs pump out laminin ...
... to understand the regulation of these key genes and the transport of their proteins to the red cell surface.
Switching of surface proteins is a key defence mechanism for malaria parasites, as well ...
... out and divide in a dish for too long. They get fat and lose key surface proteins, which interferes with their movement and reduces their therapeutic potential. Now, via a simple chemical procedure, ...