... exist where GFP or some other auto-fluorescent protein is used as a reporter for specific gene expression in Drosophila and other organisms. -Our methods should be readily adaptable to such reagents, ...
Providing another tool to help to understand gene regulation on a global scale, a nationwide research team ... previously appreciated in cell-type-specific gene expression, helping to explain what causes ...
... are clearly strong evolutionary constraints on tissue-specific gene expression. Many genes show conserved human/fish expression despite having almost no nonexonic conserved primary sequence".
...
... regulator of brown fat cell determination. PRDM is selectively expressed in BAT, where it activates brown fat-specific gene expression and represses white fat-specific gene ...
... first time researchers have identified a specific gene expression profile of prostate cancer stem ... inflammation were prominent in the cancer stem cell expression profile. Potential therapeutic target NF ...
... cells, opening a new window on how gene expression drives normal development and disease-causing ... technology to detect cell type-specific gene expression. The researchers say the method should work ...
... were dysregulated in patient samples compared to samples from healthy individuals, and also detected specific gene expression profiles that are unique to CdLS patients. Importantly, said Krantz, the ...
... combination with chemotherapy. The findings suggest that patients with tumors with a specific gene expression profile may benefit most from the incorporation of this drug into their treatment.
The ...
... a considerable part of the B cell-specific gene expression pattern. The phenotype and the characteristics of Hodgkin ... B cells. IL-21 activates a specific signaling pathway (STAT3), thus up-regulating ...
... patients whose clinical outcome was known, the researchers were able to associate specific "gene expression signatures" with particular outcomes.
The researchers are optimistic that oncologists will ...
... the study, researchers performed various tests activating LXR receptors in cells and found that specific gene expression induced by the Hh pathway could be inhibited. This finding was also confirmed ...
... regulation of growth and the development of cells. It is also crucial for cell-type-specific gene expression in various tissues. Deregulation of this system results in breast and ovarian cancer.
...
