... previously known classes of small RNAs. The new small-RNA class both modifies ... discovery of a new source of regulatory RNA in mice. Many RNA sequences, such as microRNAs, are flagged as regulatory ...
... coding" segments (called exons).
The final product of RNA splicing (called a mature messenger ... splicing often depends on the location and context of the RNA sequences they bind," Dr. Krainer explained ...
... 25,000 genes yet be so different.
"RNA offers a way to make the cell much ... without fear of losing the RNA. At the end of the day, they are left with the RNA sequence to which the protein was bound. ...
... and non-engineered viral RNA in living cells.
"The great thing about these probes is that they recognize RNA sequences and bind to them using the same base pairing most people are familiar with in ...
New technique allows single molecules of RNA to be sequenced directly without the multiple manipulations currently needed
... understood. The problem has been finding a way to mark RNA in a living cell so that scientists can track ... molecule, adding a small tail of RNA sequence that works like a handle, grabbing the fragments ...
... details of how the cell's major transcriptional machinery, RNA polymerase II (Pol II), functions ... II uses the DNA genetic sequence as a template to specify the RNA sequence, another largely unknown ...
... the genome can interact by direct contact or through intermediaries that can be proteins or RNA sequences. The exact mechanisms of how paramutagenic alleles communicate with their homologous partners ...
... . Although introns are not part of a gene's protein code and are removed from the RNA sequence before translation into proteins, they are nevertheless structurally and functionally important, as ...
... molecule called a messenger RNA. The messenger RNA sequence is then translated into the amino acid ... two. This self-cleaving action in the messenger RNAs effectively turns off the genes by preventing ...
... the specific recognition mechanisms between AIDS virus RNA and a synthetic RNA. These results should provide a basis for the development of new therapies targeting viral RNA sequences.
... distinguishing the archaeal and bacterial ribosomes is located in five percent of the ribosomal RNA sequence. Most of these molecular signatures occur in regions that are critical to ribosomal ...
... previously known HIV-1 genetic sequences, to construct a range of plausible family trees ... recovering more samples and assembling the fragmented DNA and RNA sequences to form a clearer picture of HIV' ...
... stretches of chromosomes. A highly efficient genome-sequencing technique developed several years ago ... cells to shut off specific genes.
RNA sequences that corresponded to all the 300 or so deleted ...
... . Trans-splicing therapy relies on splicing, or uniting, of mutant RNA and therapeutic RNA in order to correct RNA sequence.
To improve efficiency, the researchers developed a trans-splicing system ...
