... glycan-binding receptor, or lectin, ever discovered in animals.
“The Ashwell receptor is ‘turned on’ after birth, and this was a clue that it is needed for environmental and pathogenic challenges,” ...
... .
“This is the first example of a bacterial virulence factor that uses sphingomyelin as a receptor,” Blanke said. “Only sphingomyelin confers sensitivity to the toxin in these cells, whereas other ...
... in the wrong neurons) so that when the regulator is experimentally blocked, the related receptor appears in more neurons than it should.
Interestingly, the regulatory sequences identified in this ...
... at Baylor College of Medicine in Houston to describe how the genetic message of estrogen receptor-alpha is regulated, a finding that could have implications for breast cancer. In a report in the ...
... , hope that doctors could treat the pain that people with IBS experience by targeting and blocking this receptor.
People with severe pain from IBS are currently treated with opiates, which can have ...
... less likely to develop invasive estrogen-receptor (ER) positive breast cancer compared ... taking the drug. Raloxifene is a selective estrogen receptor modulator (SERM), which might suggest that the drug ...
... the T cell to latch onto its environment. "What we are providing here is insight into how these receptors collaborate, or 'talk' to one another," says Bunnell.
First author Ken Nguyen, a graduate ...
... don't work optimally.
In addition, other researchers have found a correlation between diminished insulin receptor signaling and Alzheimer's disease. Results of the Cold Spring Harbor team's research ...
... of neural circuits. The finding suggests a significant role for this class of receptors and perhaps for insulin, not only in brain development, but also in cognition and in pathological processes in ...
... of induction of diarrheal disease.
"There may be ways to block the interaction between the enterotoxin and the receptor to treat diarrheal disease," said Estes, who is also director of the Texas ...
... at Boston University School of Medicine (BUSM) have, for the first time, found that angiotensin receptor blockers (ARBs)—a particular class of anti-hypertensive medicines—are associated with a ...
... earlier, mainly in cell culture experiments," DuBois said. "The molecular mechanisms for loss of the receptor and its effect on cancer have not been previously shown."
First, the team found that CB1 ...
... a key role in regulating the sleep/wake cycles in mammals. The new finding demonstrates that light receptor cells in the eye are central to setting the rhythms of the brain's primary timekeeper, the ...
... at Duke reveal that the biochemical pathways linked to this receptor – the pathways along which the drugs deliver their therapeutic ... receptor pioneer Robert J. Lefkowitz, M.D., and Marc G. Caron, Ph.D ...
The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) was associated with a reduced risk of basal cell or squamous cell skin cancers in U.S. veterans, ...
