An international team led by NYU Cancer Institute have identified a protein complex that regulates the formation of cilia, which are found on virtually all mature human cells and are essential to ...
The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell. The Histone H3 protein is an important component ...
Scientists at the Stanford University School of Medicine have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body — a ...
Scientists have identified a protein complex important in controlling whether embryonic stem cells retain their ability to become any cell in the body -- a quality called pluripotency -- or instead ...
... have identified factors that can perform gene-specific DNA demethylation, but ours is the first to link a protein complex to global DNA demethylation that correlates to germ cell to somatic cell ...
Researchers have discovered a protein complex that appears to play a significant role in erasing epigenetic instructions on sperm DNA, essentially creating a blank slate for the different cell types ...
... environments. The ability to "fly" intact membrane proteins in a mass spectrometer paves the way for weighing ... Professor Robinson first flew soluble protein complexes in a mass spectrometer in 1996, she ...
... , Dean's lab was the first to discover ISC proteins. Now Dean's students, Raulfs and O' ... Fe-S clusters," said Raulfs, who first isolated a protein complex with a cluster attached, providing in vivo ...
... have shown in cells that NUP214-ABL1 is no longer carcinogenic when it cannot bind with the protein complex in the vicinity of the cell nucleus. On the basis of these results, the researchers want to ...
... with scientists from China and Singapore, have crystallized and characterized the structure of one of the most important protein complexes of the H5N1 virus, the most common strain of bird flu.
All ...
... is that information about how Mre11 works in humans can be derived from organisms in which proteins and protein complexes are much more stable at room temperature than human proteins would be. For ...
Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs New research ...
... key player – COPI (Coat Protein Complex I) transport complex, - already known to have a separate ... lipid droplet surface. An absence of some of the PAT proteins in mice or flies lead to lean animals, ...
... called inflammasomes, which are multi-protein complexes that play major roles as guardians against both ... AIM2 binds to the foreign DNA, it recruits a cytoplasmic protein called ASC. ASC and AIM2 then ...
Blocking a specific protein complex prevents the formation of tumors in mice genetically predisposed to develop prostate cancer, researchers at the Whitehead Institute for Biomedical Research have ...
