... enabled researchers at Baylor College of Medicine in Houston to describe how the genetic message of oestrogen receptor-alpha is regulated, a finding that could have implications for breast cancer...
Women who took raloxifene were less likely to develop invasive oestrogen-receptor (ER) positive breast cancer compared with women who did not, according to data from a randomised controlled trial ...
Researchers have found evidence of a statistically significant survival benefit from adjuvant tamoxifen among patients whose oestrogen receptor (ER)-positive tumours had high levels of ...
A tiny modification called methylation on oestrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's ...
... in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring oestrogen receptor in the brain may also clear cognitive cobwebs...
University of Cincinnati (UC) researchers have discovered that oestrogen receptors are present in medulloblastoma - the most common type of paediatric brain tumour - leading them to believe that anti- ...
... journal Breast Cancer Research. In this large study, aspirin use was linked to a small reduction in oestrogen receptor-positive breast cancers. However, unlike in some previous research, aspirin and ...
... 22kg/m2)
Women who were mothers, had no family history of breast cancer, were not white and had oestrogen receptor negative tumours also had a reduced risk of breast cancer.
The authors said the way ...
... subcutaneously (with patches), as well as by treatments based on substances that modulate the oestrogen receptor, amongst these being raloxifene. However, the effects of these therapies are disputed, ...
... ways of preventing oestrogen from stimulating growth. One is to block the oestrogen receptors that are present on the cells so that they can't respond to the hormone. Tamoxifen works this way. The ...
Researchers at Georgetown University Medical Centre have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and ...
... , "Anti-oestrogens, such as tamoxifen, have been the mainstay of therapy in patients with oestrogen receptor positive (ER+) breast cancer and have provided significant improvements in survival. Our ...
... Non-invasive imaging can measure how well patients with the most common form of breast cancer - oestrogen receptor positive type - respond to standard aromatase inhibitor therapy after only two weeks ...
... the inclusion of adjuvant endocrine therapy for most patients whose tumours show evidence of any detectable oestrogen receptor. Anti-HER2 therapy such as trastuzumab (Herceptin) is ...
... cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some oestrogen receptor-positive breast cancers respond poorly to tamoxifen ...