... we had came from smaller studies which only looked at the performance of these tests in detecting a limited number of chromosomal abnormalities."
After analysing the results of the chromosomal ...
... molecular machines in fruit flies that yank chromosomes, the DNA-carrying structures, apart when necessary ... sperm cells each receive the proper number of chromosomes -- not too many, not too few.
Bosco ...
... two.
"Each cell needs the right number of chromosomes. It's central to life in general and very ... would play a central role separating chromosomes in dividing cells, but no one had established a direct ...
... with fertility problems who are at risk for embryonic aneuploidy, an aberrant number of chromosomes, such as three copies of chromosome 21 that results in Down's syndrome. Therefore, little was known ...
... in chromosome number are usually caused during a biological event called meiosis, in which the number of chromosomes per cell is halved and, in animals, results in the formation of gametes or sex ...
... potential implications for cancer biology, in that inappropriate chromosomal segregation can lead to aneuploidies (cells lacking the proper number of chromosomes), which is a hallmark of many cancers.
... the progenitor species of A. suecica, Madlung and colleagues found many cells with differing numbers of chromosomes in A. arenosa; however, most cells in individuals of both diploid and tetraploid A. ...
... player known as Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth ... normal meiosis, the process of division that halves the number of chromosomes per cell, my colleagues ...
... themselves, receive too few or too many chromosomes if expression of the CHFR gene is missing or low. ... breast cancer cells often had the wrong number of chromosomes, but no one had identified any gene ...
... accurate chromosome sorting during mitosis. Mps1 therefore prevents aneuploidy, the change in the number of chromosomes that is closely associated with cancer.
Dr Patrick Eyers and his team, ...
... cancers, contributing to creation of abnormal centrosomes. These, in turn, lead to abnormal numbers of chromosomes in the daughter cells - a condition called aneuploidy.
Sen, Czerniak and others, ...
... and divides. Then, its progeny accumulate defects, including the wrong number of chromosomes or chromosomes that have exchanged pieces with each other. Those defects are hallmarks of cancer cells.
...
... genetic material that would not be seen on a regular karyotype (a depiction of the size, shape and number of chromosome and any abnormalities in them)," said Dr. Ignatia B. Van den Veyver, associate ...
... , the adaptation was accomplished not by changes in DNA sequences but largely by modifying the number of chromosomes in the cell (known as aneuploidy), which were passed on to future generations."
" ...
... the environment through human urine - causes cells in rainbow trout to have an abnormal number of chromosomes. This condition may be why many embryos fathered by exposed specimens die within three ...
