... House Ear Institute (HEI) researchers have shown that by blocking a biochemical pathway called the Notch signaling pathway, most of the supporting cells in the inner ear of juvenile mice are induced ...
Researchers have shown that by blocking a biochemical pathway called the Notch signaling pathway, most of the supporting cells in the inner ear of juvenile mice are induced to directly change into ...
... help to understand how airways form and provide insights into how interfering with Notch signaling may be potentially useful as a therapeutic intervention in respiratory diseases, such as asthma and ...
... couldn't return to normal, and the TSLP alarm signal couldn't be turned off. High levels ... communication system present in most multicellular organisms. Notch signaling ensures that skin cells grow and ...
... are "addicted" to Notch and that this study provides support for the evaluation of Notch signaling pathway inhibitors as a treatment for leukemia.
TITLE: Leukemia-associated NOTCH1 alleles are weak ...
... , so these findings prompted our ongoing research into Notch signaling and allow us to examine the cellular ... findings, the UCSF team now considers Notch a strong candidate as a key regulator of human ...
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ONCOLOGY: Take it down a Notch(1): new role for Notch1 in facilitating ... development, Notch1. These data suggest that targeting the Notch signaling pathway might provide a new ...
... and inhibited by interferon gamma. This subset of genes included genes that are involved in the Notch signaling pathway. For some time, scientists have known that the Notch signaling pathway regulates ...
... Notch activity is a key determinant of the cellular development and differentiation related to this process. As Notch signaling is activated in human breast cancer, (and a negative regulator of Notch ...
... treatment of IPF.
TITLE: WNT1-inducible signaling protein䂿 mediates pulmonary fibrosis in mice ... disrupts the activity of a molecule known as RBPJ in the Notch signaling pathway, causing abnormal fetal ...
The Geneva-based World Health Organization on Wednesday raised its alert level for the fast-spreading swine flu to its next-to-highest notch, signaling a global pandemic could be imminent.
... level of its expression and the percentage of breast cancer stem cells, suggesting that Notch signaling may play an integral role in the development of breast cancer stem cells.
Reuben will present ...
... in Bellen's laboratory, identified a mutant with a cluster of neurons. This occurs when there is a problem in Notch signaling.
Ordinarily, the sensory organ progenitor cell uses the Notch pathway to ...
... EGFL7 stimulated the differentiation of neural stem cells into neurons.
„ It has been well defined that Notch signaling drives the formation of astrocytes from neural stem cells while it suppresses ...
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NEPHROLOGY: 'Notch'ing up our knowledge of kidney development
TITLE: Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice
AUTHOR CONTACT ...
