... Clinic and a doctoral candidate. "By crossing these mice with a mouse strain that ages five times faster than normal due to a mutation in the BubR1 gene, we were able ...
... Schwartz examined the susceptibility of different inbred mouse strains for developing invasive aspergillosis after receiving immunosuppressive therapy. The inbred strains exhibited significant and reproducible differences in survival ...
... . What's worse: the thawed sperm of the most popular mouse strain in the scientific world, the C57BL/6 ... is that it costs about $10,000 a year to maintain a particular mouse strain, and worldwide only a few hundred ...
... , Dr. Goldstein used his HIV-TG mouse strain, in which HIV is known to replicate inside ... -producing monocytes from the HIV/GFP-TG mouse strain. Four days later, HIV-producing monocytes could be detected in the brains of about 25 percent ...
... responses. In addition, they discovered that Rfv3 susceptible mouse strains that fail to make antibody responses have a natural defect in Apobec3. These results provide convincing ...
... 's technique uses another animal strain called the leptin-luciferase mouse, in which the visibly detectable marker ... of the promoter of the gene that produces the hormone leptin. In this mouse strain the luciferase marker gene only switches ...
... of genes that had previously shown to be differentially expressed in mouse strains that differed in their innate anxiety levels. The authors then studied groups of humans with anxiety ...
... closely resembling the one predisposing humans to the disease. The other strain of mice, known as NOD.B10, has had its chromosomal ... weeks, always comparing like tissues from one mouse strain to the next at the same stage of life ...
... , and the proteins' powers in vivo remained uncertain. Aucott et al. created the first mouse strain missing one of the HP1 versions, HP1b. The animals die shortly after birth because their lungs ...
... resource for this finding, Oliver's team used a special mouse strain in which the Prox1 genes could be deleted from LECs at different times during development or after birth. The St ...
... neurodegenerative disorders. Wilcock and Colton describe the mouse studies of anti-amyloid-β immunotherapy and how they relate ... and colleagues presents the senescence-accelerated prone mouse strain 8 (SAMP8) as a model of early AD and mild cognitive impairment. Two new ...
... of Mre11 in the MRN complex. They engineered two mouse strains, one in which Mre11 was disabled completely, and one in which only a single amino acid change was made. What surprised ...
... , roughly doubles in weight over its adult life. That strain benefited from caloric restriction, Sohal said. The "lean ... said. Studies of caloric restriction in wild types of mouse strains have shown minimal life span ...
... Ana Carnerio, Ph.D., discovered that a mouse strain they had been using to studying SERT function – called ... an online resource called the Mouse Phenome Database, they found that most mouse strains possess a SERT version ...
... of the foot shock, observers from a very social mouse strain learned from the distress calls to associate ... say. Future studies will focus on the genetic differences between the mouse strains to try to identify some of the specific genes ...
