... and basically empower them so women have some preventive measure that's under their control."
Microbicides are compounds that can be applied inside the vagina to protect against HIV and other ...
... antiviral drug valacyclovir can help minimize symptoms and reduce the risk of transmitting the virus.
The microbicide in this study is based on RNA interference (RNAi), a mechanism cells use to ...
Finding a microbicide is one of the thorniest problems in AIDS research.
... prevent HIV infection, women often cannot negotiate condom use with their male partners. An effective microbicide could provide women with an HIV prevention method they initiate.
HPTN 035 evaluated ...
... 3,000 women in the US and southern Africa demonstrates for the first time the promise of a vaginal microbicide gel for preventing HIV infection in women. According to findings, one 0.5 percent dose ...
... and the senior researcher involved in the work. "A vaccine is still some way off, but microbicides could provide a more immediate solution, provided we can overcome major hurdles of high efficacy, low ...
A microbicide has shown promise in the lab and can be produced in plants — a double blow toHIV in the developing world, scientists say.
... trials after passing laboratory and animal safety tests. But with just one exception, all the microbicides were found to be ineffective against HIV; and two of the gels — nonoxynol-9 and cellulose ...
Scientists have devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researchers have also discovered why several supposedly "safe" microbicides made ...
... of other STIs has had discouraging results; vaccine development trials and microbicide testing have been disappointing; and abstinence is not likely to have a major impact since most HIV infections ...
Clinical trials hoping to identify a vaginal microbicide that is safe and effective against HIV have all but skirted questions befitting evaluation of an approach intended primarily for sexually ...
... Dr. Julio Montaner and colleagues in CMAJ. Despite advances in HIV treatment such as topical microbicides, pre- and post-exposure treatment and male circumcision, HIV infections continue to increase ...
... gel to be used daily. But ARV-based prevention approaches are not without scientific and practical challenges. The Microbicide Trials Network (MTN) is taking aim at among the most pressing of these ...
... the HIV virus. The main question now is if this can be applied to developing vaccine and possibly used as a microbicide to prevent sexual transmission," said David C. Montefiori, Ph.D., director of ...
Researchers are conducting far-reaching trials to determine whether existing treatments can be used prophylactically to block infection. ...
