Science news articles about 'hiv protease'

... cells in the eye (known as photoreceptors) after retinal detachment. In the study, administration of HIV protease inhibitors by mouth markedly decreased photoreceptor apoptosis in the mouse model of ...

... ABC-transporter mediated efflux mechanisms decreased intracellular concentrations of the anti-HIV drugs, saquinavir, an HIV protease inhibitor (HPI) and zidovudine, a nucleoside reverse transcriptase ...

... lab that the compound does indeed inhibit HIV protease, which is an established target for AIDS treatment ... flap recognition pocket, and actually holds the protease open. Scientists knew the flaps opened ...

... infectious, but require the two clamshell halves to bind together to be activated, according to the paper. The HIV protease was successfully targeted for drug development in the 1980s, by blocking ...