... or so molecules. Given that academic and corporate researchers alike now rely on high-throughput screening of up to hundreds of thousands of molecules to accomplish many of their goals, that's a ...
... HeLa cells. They found the technique speeded analysis by several orders of magnitude.
In high-throughput screening processes used for drug discovery and other research, tens of thousands of wells — ...
... for functional studies. They further used the kinome collection in several high-throughput screens, including a screen which identified two novel kinases regulating the Hedgehog signaling pathway – a ...
... the mutated PAH protein in individuals with PKU such that it can function normally.
In the study, a high-throughput screen for small molecules that stabilized mutated forms of the PAH protein found ...
... the mutated PAH protein in individuals with PKU such that it can function normally. In the study, a high-throughput screen for small molecules that stabilized mutated forms of the PAH protein found in ...
... .
Dr. Lum noted that the findings about TCF7L2 show the effectiveness of this high throughput screening technique, which can quickly and systematically check many thousands of genes.
The success of ...
... UCSF's patented ViroChip technology.
The ViroChip, which DeRisi and Ganem developed, is a high-throughput screening technology that uses a DNA microarray to test viral samples. The team was able to ...
... fighting at least three pathogens and likely many more."
Identifying LED209 was accomplished by using a high throughput screen of 150,000 compounds in UT Southwestern's Small Molecular Library. The ...
... to, or removed from, the crystal surface. The measurement technique can be used, for example, in a high-throughput screening mode to rapidly identify molecules and compounds that prevent DNA-protein ...
Silicon diving boards used as high-throughput screening arrays to study action of antibiotics
... Titorenko and his colleagues developed a life-span assay for a high-throughput screening of multi-compound chemical libraries.
The assay identified five groups of novel anti-aging small ...
... The enzyme that makes fireflies glow, called luciferase, is widely used in biomedical experiments and in high-throughput screening often utilized to discover drugs. In a positive reaction, the tested ...
... wouldn't see using traditional genetic screening methods. Finding these correlations gives us ... Chicago, there are many detours people could take. Using high-throughput screening allows us to step back ...
... that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques. The study, based on screening large numbers of chemical ...
... with Dr. Fraser Glickman at Rockefeller University's High Throughput Screening Resource Center, developed a screening test that substituted a non-lethal cow virus for the real thing. They ...
