... the data, but the image analysis toolbox is expanding at a remarkably fast rate. This is the beginning of high throughput systems biology.”
Maureen Mancini, a research associate at BCM, helped ...
... and cellular biology at BCM and director of its Integrated Microscopy Core. "For example, we could use the high throughput microscope and robust image analysis to determine which drug might be best ...
... hundred or so molecules. Given that academic and corporate researchers alike now rely on high-throughput screening of up to hundreds of thousands of molecules to accomplish many of their goals, that's ...
... University of Colorado at Boulder report technical advances that will dramatically accelerate the process for high-speed "color" ultrastructure brain mapping. The advances include software to build ...
... /, promises to enable higher accuracy analysis of the microscopic images produced by today’s high-throughput biological screening methods, such as the ones used in drug discovery, and to help decipher ...
... activity that are necessary for functional studies. They further used the kinome collection in several high-throughput screens, including a screen which identified two novel kinases regulating the ...
... in order to thrive.
Research continues. “It took us 10 years to get where we are now. With the new high-throughput technology now available, we will complete a high-resolution genetic ...
... 'll work with The Scripps Research Institute in Jupiter, Fla., to expedite the required high-throughput analysis.
One of the families that provided the sentinel genetic information had 15 members, ...
... the analysis of human cancers."
The project was made possible by the Sanger Institute's high-throughput sequencing and computational resources, which allowed the team to identify new potential ...
... ) that are critical for maintaining the embryonic stem (ES) cell state. Using advanced high throughput sequencing technology, the scientists discovered over 3,000 hotspots. These findings could ...
... chromatography-tandem mass spectrometry. This method has incredibly high sensitivity (down to 1 ng/ml) ... (DOI: 10.1002/jms.1448) A High-Throughput Multicomponent Screening Method for Diuretics, ...
... minimal sample preparation and requires no labeling with radioisotopes. The technique also offers relatively high throughput sample analysis, which enables researchers to image many cells quickly.
" ...
... ."
Pelletier's lab at the Department of Biochemistry and McGill Cancer Centre focuses on high-throughput assays of various compounds to determine their anti-cancer effectiveness. One that showed ...
... to stabilize the mutated PAH protein in individuals with PKU such that it can function normally.
In the study, a high-throughput screen for small molecules that stabilized mutated forms of the PAH ...
... to stabilize the mutated PAH protein in individuals with PKU such that it can function normally. In the study, a high-throughput screen for small molecules that stabilized mutated forms of the PAH ...
