... and purification capabilities."
A tantalizing observation made during the determination of the glucose transporter structure was the possibility for structural similarities with a previously ...
... have solved the structure of a class of proteins known as sodium glucose co-transporters, which pump glucose into cells. The solution of the SGLT structure will accelerate development of new drugs ...
... high-capacity urate transporter, and thus possibly a new drug target for gout. Their findings ... people with normal levels. SLC2A9 encodes a glucose transporter (a protein that helps to move the sugar ...
... means of a system known as the GLUT4 glucose transporter.
Normally, she said, GLUT4 is stored inside ... cells also form a GLUT4 compartment and take up glucose in response to insulin. In type 2 diabetes ...
... levels by stabilizing the sodium/glucose transporter 1 (SGLT1) via a kinase-independent mechanism. ... kinase activity, maintains the basal intracellular glucose level and thereby prevents cancer cells ...
... Canada. Their study, entitled Genetic Variant in the Glucose Transporter Type 2 (GLUT 2) ... fructose (simple sugar such as corn syrup) and glucose (carbohydrates), regardless of age or sex.
the two ...
... on the surfaces of the artificial viruses should improve binding of the artificial virus to the glucose transporters on the surfaces of the target cells. These transporters are present in nearly all ...
... glucose and insulin.
The entire two-session process was repeated 7-10 days later. ... signaling proteins believed to play a role in glucose transport into the muscle were elevated to a greater extent ...
... low-active animals in peripheral (muscle) tissue," Lightfoot said. "So the suggestion that by over-expressing a glucose transporter we can increase activity doesn't seem to be the explanatory factor." ...
... walls of the portal vein system detect the glucose and inform the brain," he said. "It's an important signal ... mice lacking GLUT-2, a glucose transporter required for glucose sensing in the portal vein ...
... of Medicine and Dentistry shows that the SLC2A9 gene, which encodes a glucose transporter, is also a high-capacity urate ... (2008) SLC2A9 is a high-capacity urate transporter in humans. PLoS Med 5(9): ...
... fat tissue to take up glucose from the bloodstream by stimulating a known glucose transport pathway. Specifically, apelin activates a pathway including an enzyme called AMP-activated protein kinase ( ...
... by helping the transporters slide into the surface membrane.
In healthy people, around 80% of the glucose transporters migrate to the cell membrane after a meal, allowing plenty of glucose into the ...
... of a hormone called adiponectin as well as the insulin-sensitive glucose transporter 4 (GLUT4), they report.
Genetically altered mice that lack CREB in fat cells become more ...
... Cartee said.
The results suggest that the protein TBC1D1 was more important for exercise-stimulated glucose transport and suggested that the second protein, AS160, might be less important for this ...
