... for the best results.”
“We are excited about the success of this work and the prospects it holds for future drug development,” said USAMRIID principal investigator S. Ashraf Ahmed, who initiated the ...
...
"This broadens the notion of what drugs can do, and therefore, has wide reaching implication for future drug discovery for many different disorders," Dr. Golde says.
The findings also suggest that ...
... Chemistry has exposed one of the tricks malaria uses to hide from the immune proteins, which may aid in future drug development. Malaria parasites (plasmodia) are transmitted to people via infected ...
... risk from prescription drugs and suggests institutional reforms to help avoid or reduce future drug disasters.
According to Light, rather than using current approved drugs as benchmarks of efficacy, ...
... an enzyme called Brk that may serve as a target for future drugs developed to fight ErbB2-positive ... speed," he explained.
How Brk is implicated in drug resistance
Aside from hurrying along tumor ...
... century old "Overton's Rule". This could have major implications for the development and testing of many future drugs. Overton's rule says that the easier it is for a chemical to dissolve in a lipid ...
... universities have joined forces to develop new ways of building state-of-the-art chemical libraries that will help identify new compounds for future drug development and basic biomedical research.
... trypanosomal enzyme, can now serve as the basis for future drug design and discovery efforts.
McCammon's ... method to identify promising drug candidates for treating H5N1 avian flu.
McCammon's team is ...
... .
The scientists agree that a major clinical and ethical challenge will be how to safely test future drug development in humans since current antiretroviral therapy is so effective and relatively ...
... -independent mechanisms underlie antidepressant actions. "The big unanswered question is whether future drugs that directly stimulate neurogenesis will be as effective as popular antidepressants or ...
... involved in nerve transmission," says Furukawa. Its uniqueness makes it a potentially interesting target for future drugs. "Our interest is even keener because we already know there are a rich ...
... also an associate professor of medicine at Harvard Medical School. It also provides numerous targets for future drugs aimed at restoring the normal balance of signals among these genes.
"Our results ...
... could allow pharmaceutical companies to someday design drugs to regulate iron levels in the blood.
“Iron is ... to fit those spots like puzzle pieces.
If a future drug fits those nooks just right, it ...
... an innate block that otherwise prevents viral replication.”
By implication, this suggests a strategy by which a future drug might interfere with the reproductive machinery of the virus to prevent or ...
... this signal, and this pathway is therefore a very good target for future drug development" said Junping Wei, M.D., Ph.D., a researcher at Cincinnati Children's and lead author ...
