The use of doxorubicin followed by zoledronic acid reduced tumor size substantially in a mouse model of breast cancer that does not have bone metastases.
... University, demonstrates that the growth inhibitory activity of doxorubicin or cisplatin, as single agents, may be modified in combination ... (DRI) at the IC50 demonstrated possible reductions in doxorubicin concentrations for the drug combinations, ranging from 1 ...
... combines three chemotherapy drugs (cyclophosphamide, doxorubicin and vincristine) with the steroid drug prednisone and rituximab ...
... to cytotoxic chemotherapy drugs. Some cytostatic drugs, such as doxorubicin, induce NF-κB pathway activity ... with melanoma cells and then treated them with doxorubicin and KINK-1. They found that mice treated with a combination ...
... to cytotoxic chemotherapy drugs. Some cytostatic drugs, such as doxorubicin, induce NF-ºB pathway activity ...
... rounds of targeted chemotherapy using the drugs cisplatin and doxorubicin via surgically implanted catheters. Some patients ...
... which had already demonstrated resistance to the chemotherapy agent doxorubicin. "Essentially, we have turned off the cancer cell ...
... – which delivers the cancer cell-killing drug doxorubicin to the network of blood vessels supporting the tumor that express the ανβ3 protein. "Doxorubicin is known to be an effective anti-cancer drug, but has been difficult to give ...
... . With their approach, the Wooley lab was able to load more doxorubicin into the cores of the nanoparticles, compared with similar constructs ... , who worked on the project. However, the nanoparticles carrying the doxorubicin were not as effective at killing cancer cells compared ...
... agents acting via mitochondrion, including doxorubicin, a common drug in chemotherapy. This research has been developed ...
... and multiply. By interfering with topoisomerases in cancer cells, doxorubicin and other drugs in the same class including etoposide ... with the finding that Top1 knockdown hypersensitized cells for doxorubicin treatment, this result suggested to the CSHL researchers ...
... . Oncologists frequently use anthracyclines, including epirubicin and doxorubicin, to treat breast cancer patients. However ...
... cancer patients are also frequently treated with the anthracycline doxorubicin. Previous preclinical studies have suggested that the combination ... complete destruction of the tumors. Sequential therapy with doxorubicin and zoledronic acid was shown to increase the fraction ...
... hold, along with the anti-cancer drug doxorubicin. The iron oxide nanoparticles allow the ships ... and magnetic nanoparticles, quantum dots and the drug doxorubicin are the nuts. They sail through the bloodstream in groups ...
... the new drug trabectedin with pegylated liposomal doxorubicin provides clinical benefit to women with relapsed ... weeks, the remainder received pegylated liposomal doxorubicin 50 mg/m2 alone every ...
