... to look at what happens when you make the receptor more sensitive and thus put the dopamine system into overdrive. "We were able to not only isolate this receptor's function, but also to amplify it," ...
... as an addictive disorder. This is the first study to demonstrate that obesity predisposition is associated with impairments in all midbrain dopamine systems that are in place early in postnatal life.
... .
The researchers used the imaging technique positron emission tomography to study the changes in the dopamine system that occur with sleep deprivation. Compared to well-rested participants, sleep- ...
... up to 72 hours after ingestion of diazepam. "Our studies have shown that diazepam also affects the dopamine system, which adds a new positive reinforcement mechanism of reward learning to the theory ...
Brain-scanning study in people sees link between personality, dopamine system
... conclude. "These findings reveal important mechanisms that underlie the regulation of the mesolimbic dopamine system by a crucial signal of energy stores. In the future, it will be crucial to address ...
... undergone treatments, or had a history of drug abuse or other conditions that can affect the dopamine system.
To strengthen the statistics and control for these factors, the current study looked at ...
... some other means."
According to the dominant hypothesis, schizophrenia is related to an overactive dopamine system. Previous studies have shown that interleukin-1beta can upset the dopamine system ...
... by such influences," says Anderson. Importantly, ADHD has been genetically linked to abnormalities of the dopamine system in humans, further strengthening the analogy between the mutant flies and this ...
... were injected with a radioactive compound that binds with elements of the brain’s serotonin and dopamine systems. Once administered, the radiotracer revealed functional alterations in these systems ...
... of relapses of methamphetamine addiction, but potential therapeutic agents targeted to dopamine and non-dopamine systems are in clinical testing.
"Research into the pharmacologic treatment of ...
... signals related to nicotine's rewarding properties. This pathway is called the 'mesolimbic' dopamine system and is involved in the addictive properties of many drugs of abuse, including cocaine, ...
... pregnancy are at greater risk of ADHD," Wilens says. "It looks like interplay between the dopamine system, more substantially related to ADHD and addiction, and the cholinergic system related to ...
... with the brain's pleasure system.
"In these obese rats, like in humans, the dopamine system is suppressed and it is very possible that the obese rats are seeking a hedonistic experience or reward by ...
... on reward systems in mammals, including humans. It does this by influencing the chemically related dopamine system.
Dopamine plays a role in the human ability to predict and respond to pleasure or ...
