Science news articles about 'cilium'

... cilia. "The really important discovery is that the primary cilium detects signals, which tell the cells to engage ... explains. "In mutant cells that lack the primary cilium," Christensen says, "cell migration is unregulated with uncontrolled ...

... primary cilium, the solitary, antenna-like structure that studs the outer surfaces of virtually all human ...

... , measured the diffusion coefficient of a protein in a primary cilium and in other major compartments of a highly polarized cell ... (photoactivatable green fluorescent protein) in the connecting cilium (CC) of retinal rod photoreceptors in frogs ...

Scientists have, for the first time, measured the diffusion coefficient of a protein in a primary cilium and in other major compartments of a highly polarized cell.

... ). And, as you might guess, it all hinges on the primary cilium. Specifically, the researchers have discovered that genetic mutations ... and other proteins from the cell's membrane to the surface of the primary cilium. "This provides a very logical explanation for the wide ...

... , and then there is the until recently mysterious primary cilium.Nearly all human cells contain these numerous ... , cells also contain a single, nonmotile cilium known as the primary cilium. Its presence on cells has been known ...

... of signaling molecules that normally reside at the primary cilium, may lead to certain cancers." At the center of the process ...

... inside the human body. The problem is that each cilium finger must be very flexible in order ...

... that the enzyme goes to a cellular structure known as the cilium, a long-forgotten organelle without clear ... bodily functions are regulated and "fine-tuned" by the cilium. Because all of the genetic mutations led to an alteration ...

... that Hedgehog prompts the Smoothened protein to head to the cilium where it knocks out a Gli "repressor," thereby ... division because its repressor is not in place to restrain it. "The cilium doesn't appear to just turn ...

... with. When one particular mutated protein was activated, removal of the cilium prevented the onset of disease; when another particular ... were removed. The explanation may be, the researchers say, that removing the primary cilium prevented it from carrying out one of its other jobs – activating proteins ...

... or propel the cell forward. Each flagellum (or cilium) has nine pairs of fused microtubules, called ...

... .jcb.org). Although Arl13b—which is required for cilium biogenesis and embryo development—is known to be mutated ... membranes, where it regulates ciliary transmembrane protein localization and transport of proteins to the tip of the cilium ...

... polymerization, was applied to one of the identified proteins, it repaired cilium formation in cells carrying mutations. "While ...

... in fine "tip links" that tether each cilium to its neighbor, causing them to pull open ...