... something very unexpected in their studies of the worm C. elegans: Authority is taken away from individual ... any cell in the organism without them. (C. elegans is a transparent roundworm whose genome, ...
... these occur, will help to understand the cause behind these changes and contribute to understand C. elegans (and human) genes, as well as the mechanisms behind disease and health. In fact, Alzheimer' ...
... , Ashrafi and his team began analyzing serotonin-induced regulation of fat and feeding in the microscopic C. elegans worm. They took advantage of a powerful and relatively ...
... accumulation, the researchers noted. However, there are some differences. In C. elegans, when serotonin goes up, feeding goes ... eat less and shed fat.
Since C. elegans directly match their feeding rates ...
... . Hiroshi Tsuda, took over.
One of the domains of VAPB is similar to a protein in C. elegans called the major sperm protein (MSP). MSP plays a major role in readying the hermaphroditic worm ...
... from generation to generation.
Its patterns of mutation, however, turned out to be unique. While C. elegans mutations were largely the result of inserting or deleting base pairs of DNA, yeast's ...
... and sorts it into the appropriate group.
Initial tests to assess the system were conducted on C. elegans, one of the tiniest multi-cellular organisms that share many fundamental cellular/molecular ...
... . Sir2 controls aging and life span in yeast, the worm C. elegans, and Drosophila fruit flies, earlier studies have shown.
Studies have also implicated Sir2 in the life-extending effects ...
... identify the sex pheromone that attracts male C. elegans worms to the more common hermaphrodites (this worm ... species has no females). C. elegans, a tiny nematode, is a model organism often used to study ...
... author of the research.
Kim's lab examined the regulation of aging in C. elegans, a millimeter-long nematode worm whose simple body and small number of genes make it a useful tool ...
... In 2002, Cal Tech researcher Paul Sternberg, Ph.D., discovered that male C. ... signaling has been poorly understood. We wanted to understand how C. elegans talk to each other, basically."
About four ...
... that strongly attracts males. When males are exposed to the chemical, dubbed "worm sweat" by C. elegans researchers, "males will act as if their desired mate is near, and start blindly feeling around ...
... chief among them that exposing paralyzed C. elegans to ultraviolet light restored normal ... them. The same response had not been found previously in normal C. elegans because those worms have no trouble ...
... more traditional adult invertebrate model systems such as the fruit fly Drosophila and the nematode C. elegans. This research will be published in the journal Disease Models & Mechanisms available ...
... , which decreases the action of pha4/FoxA down the line, and that in turn shortens the lifespan of C. elegans," says Mango. "When there's little food, there's little TOR and more pha4/FoxA, and that ...