... of the body are associated with preterm birth. However, though there has been evidence suggesting brain malformations are also associated with preterm birth, it has been difficult to document such an ...
... 's Research Hospital scientists have identified one of the molecular mechanisms underlying the genetic brain malformation called holoprosencephaly (HPE). The findings not only yield insights into the ...
... a person to navigate by following a route without getting lost.
Brain malformations or lesions in parts of the brain important for navigation are known to cause navigation difficulties. However, no ...
... Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics. Sonic hedgehog ( ...
Researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations.
... states that "understanding the HIPPO path may bring insights to human brain malformations. There are a number of brain size defects for which we are considering a follow up, including microcephaly ...
... of FOXC1 in Dandy-Walker malformation.
"These patients were essential for blaming the brain malformation on the FOXC1 gene," Millen said. "Based on the mouse mutants we had a huge suspicion it had ...
... been shown to cause the rare brain disorder lissencephaly, which is characterized by brain malformations, seizures, severe mental retardation and very early death in human infants. The findings offer ...
... analyzed DNA from a child with multiple congenital problems, including developmental delay and brain malformations. They found 35 CNVs, of which 32 were previously detected in healthy controls. Two of ...
