... cancer. In colon cancer, previous studies suggested association between the feature of nuclear beta-catenin, which remarks an activation of the Wnt-signaling pathway, and poorer survival. However, a ...
... . Reporting in Alcoholism: Clinical and Experimental Research, the scientists said that a protein known as beta-catenin that is involved in cell signaling and development is found at higher levels in ...
... , and the activation of a cell signaling pathway called beta catenin.
Wu and her team currently are testing therapies that target the alterations they discovered, hoping to interrupt ...
... Discoveries about Adult Stem Cells:
Sangiorgi and Capecchi took beta catenin – a gene product often found in colon and digestive cancers – and activated it in adult stem cells from the ...
... built-in genetic system that could increase the levels of beta-catenin, but only in response to a specific drug trigger ... Control mice without high levels of beta-catenin expression experienced no damage ...
... occur for tumors to become fully malignant.
To determine which genes control the production of beta-catenin and are involved in the proliferation of colon cancer cells, the research team ran three ...
... in the ascending and transverse colon. Similar observation was reported for beta-catenin, but not for alpha-catenin. There is increasing evidence to suggest that molecular mechanisms and molecular ...
... gene so that the cell can't make beta-catenin protein. She injected the virus ... forming memories of emotionally charged events.
"We found that after beta-catenin is taken out, the mice can still learn ...
... , scientists have revealed. An apparent 'hub' for changes in the connections between brain cells, beta-catenin could be a potential target for drugs to enhance or interfere with memory formation...
... molecules known to be involved in transforming the primordium into testis or ovary. This molecule, beta-catenin, is an important regulator of cell proliferation and differentiation. When it functions ...
... December 10, 2008, doi: 10.1073/pnas.0808393105)*. The gene regulator beta- ... infarction much better than those animals with a functioning beta-catenin gene. An important contribution to this project ...
... -3 integrin was required for the formation of the pY654–beta-catenin/pSmad2 signaling complex and the initiation of ... utility of such approaches.
TITLE: Epithelial cell alpha-3-beta-1 integrin links ...
... that cells from those without the disease had low levels of beta-catenin, a protein that enters cell nuclei and activates certain genes. Beta cells from people with type 2 diabetes had ...
... specific for the changed gene expression eliminates the cancer in the patient."
"Downregulating beta-catenin and GSK deregulation may have other implications in many cancers," Jamieson said. "By ...
... also linked to increased levels of a signaling protein called beta-catenin, which is known to play a key role in cancer development.
Researchers believe ATDC has potential as a ...
