... , whipworm, and other worm-based parasitic infections. Previous research has shown it to have some antitumor activity in lung and adrenocortical cancer.
"Our ability to identify novel treatments for ...
... has great potential against other cancers as well," said Dr. Von Hoff.
Abnormal activation of the Hedgehog signaling pathway appears to be an important mechanism for many different types of cancers ...
... , M.D., Center for Medical Genetics, Ghent University Hospital in Belgium, and colleagues evaluated the antitumor efficacy of nutlin-3, a potent and selective antagonist of the p53–MDM2 interaction.
...
Drugs known as HDAC inhibitors, which have antitumor activity and can be used to treat some forms of skin cancer and some types of leukemia, are also known to have anti-inflammatory properties, but ...
... new tumor blood vessels from forming and targeted existing tumor blood vessels. Importantly, all antitumor activities of argyrin A depended on expression of p27kip1 and resistance to argyrin A was ...
... .
Mouse model studies of chemotherapy-sensitive and chemotherapy-resistant models showed considerable antitumor activity both with TG2 siRNA alone and in combination with docetaxel chemotherapy. The ...
... the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis for ...
... , hepatoma, and chorioepithelioma with S. barbata extracts. However, the underlying mechanism of the antitumor activity of S. barbata extracts remains unclear. A research article to be published on ...
... Sankyo researchers discovered RS5444 in a screen for antitumor activity and then sought help from Mayo ... PPAR-gamma protein in cancer cells and activates RhoB transcription, causing expression of RhoB ...
... Stat3 contributes to the survival and proliferation of cancer cells. Activated Stat3 suppresses antitumor activity by stimulating immunosuppressive factors and by inhibiting expression of chemicals ...
... these diseases and developed an FGFR3-targeted antibody that had potent antitumor activity in mice transplanted with either human bladder cancer cells or t(4;14)-positive multiple ...
... target for these cancers and describes the development of an FGFR3-targeted antibody that had potent antitumor activity in mice transplanted with human tumor cells expressing either too much or ...
... a powerful, high-affinity α-7-nAChR inhibitor, induces antitumor activity against NSCLC by triggering apoptosis," wrote Dr. Russo. "The prolonged survival of α-CbT-treated animals ...
... inhibitory effects of Alisol B acetat and determined its mechanism of antitumor activity in human gastric cancer cell line SGC7901. Professor Li and his colleagues found that ...
... during wear.
Insufficient anti-Acanthamoeba activity in Advanced Medical Optics Complete MoisturePlus ... Anti-GRP antibodies have displayed promising antitumoral activity and DNA vaccines targeting GRP ...
