... problems in treating cancer is the propensity of tumors to develop resistance to a wide range of anticancer drugs. Over 70 percent of ovarian cancer patients, for example, have drug-resistant tumors ...
... 20 years ago, emerged in our search for platinum anticancer drug candidates with cellular uptake properties ... , co-lead author of the paper.
cDPCP's anticancer activity was first observed in mice 20 ...
... some cases of acute leukemia makes the disease more susceptible to high doses of a particular anticancer drug. The findings, from a Cancer and Leukemia Group B clinical cooperative group study led by ...
... very important to monitor patients' cardiovascular health when using this type of anticancer drug," says senior author David Ornitz, M.D., Ph.D., the Alumni Endowed Professor and ...
Drugs known as HDAC inhibitors, which have antitumor activity and can be used to treat some forms of skin cancer and some types of leukemia, are also known to have anti-inflammatory properties, but ...
... line treatments is beyond dispute; the problem with these drugs arises when cancer cells somehow become ... them.
"If we want to get better results with anticancer drugs like doxorubicin," said Dr. Lowe ...
... the mitochondria from extensive damage, thus saving the cell," Heaney said. "And whether directly or not, all anticancer drugs work to disrupt the mitochondria to push cell death."
Heaney says that ...
In pre-clinical studies, vitamin C appears to substantially reduce the effectiveness of anticancer drugs, say researchers at Memorial Sloan-Kettering Cancer Centre...
... and enough compounds to support a broad program of screening in the quest for new antiviral and anticancer drugs containing essential boron components," said Lesnikowski. There was also scope for ...
... of natural products known bacterial aromatic polyketides, which include important antibiotic and anticancer drugs. Natural products are pharmacologically or biologically potent chemical compounds ...
... have built a microfluidic device that can mimic these chemical and physical barriers, providing researchers with a new screening tool that may help with the design of more effective anticancer drugs.
... . When applied to medicine, the tiny vessels can potentially carry a sizable "cargo" of anticancer drugs or medical-imaging agents, and could be steered via antibodies and biological molecules to ...
... in a preliminary study and case report describing positive responses to an experimental anticancer drug in a majority of people with advanced or metastatic basal cell skin cancers. One patient with ...
... derivatives are used in several commercially available pharmaceutical products such as the anticancer drugs etoposide, teniposide, and etopophos, which are used in the treatment of small-cell lung ...
... involved in the cellular response to N-BPs, opening up opportunities for the development of new anticancer drugs. Daniela Delneri, from the University of Manchester, UK, worked with Gianluca Tell and ...
