Drinkers with the alcohol dehydrogenase 1C1 gene are at greater risk of colorectal cancer

Chronic drinking is a risk factor for colorectal cancer, possibly through the effects of acetaldehyde, which is created by the alcohol dehydrogenase (ADH) enzyme. This study investigated if a polymorphism of the ADH1C gene that is found in Caucasians may effect acetaldehyde concentrations. Findings confirm ADH1C1 as a genetic risk marker for colorectal tumours among people who drink more than 30 grams of alcohol per day...

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