Chemists develop new strategy to synthesize molecule that could help mitigate cancer tumor development

Researchers have successfully achieved a formal total synthesis of cortistatin A, a molecule which could help mitigate the growth of cancer tumors.

Protective effect of genetically modified cord blood on spinal cord injury in rats

Researchers genetically modified cord blood which managed to increase tissue sparing and numbers of regenerated axons, reduce glial scar formation and promote behavioral recovery when transplanted immediately after a rat...

Inflammatory factors cause damage to back of eye following keratoprosthesis implantation

Researchers have identified inflammatory factors that contribute to optic nerve damage following keratoprosthesis implantation in a mouse model, a new report outlines.

Ditch 'colonial' thinking to boost access to surgery for world's poor, rich nations told

Rich nations 'must abandon colonial narratives' and work alongside low and middle income countries to boost access to safe and affordable surgery for the world's poor, concludes an international blueprint...

Cancer thwarts treatment by 'stealing' blood vessels

Cancers can resist treatment by 'stealing' blood vessels from nearby tissues, a new study shows. The important new study is the first to show that tumors can become resistant to...

Traditional skin tests used to predict allergies to antibiotics are useless, say researchers

Skin tests traditionally used to predict allergies to amoxicillin, one of the most commonly prescribed antibiotics in children, are ineffective according to a new study. The findings determined that oral...

Everything you eat is made of chemicals

We are routinely warned by earnest websites, advertisments and well-meaning popular articles about nasty "chemicals" lurking in our homes and kitchens. Many tout the benefits of switching to a "chemical-free...

Nine things to know about animal vaccine development

Animal diseases pose significant threats to health and food security. Here are nine things to know about animal vaccine development according to three Kansas State University scientists involved in vaccine...

FSU's Dalvin Cook has shoulder surgery

The Sports Xchange Florida State running back Dalvin Cook had surgery on his shoulder earlier this week but is expected to be ready for preseason practice in August.

Venus Williams loses in Charleston

The Sports Xchange Third-seeded Venus Williams has been eliminated from the Volvo Car Open at Charleston, S.C. before the quarterfinals begin.

Report: Villanova's Jay Wright is the target of the Phoenix Suns

The Sports Xchange Jay Wright won a national title, and he's becoming popular in the NBA coaching rumor mill.

Study: Happy marriage may prompt men to get colonoscopy

HealthDay News Older men are more likely to get a colonoscopy to screen for colon cancer if they're happily married and have a highly educated wife, according to a new...

Baylor prospect Shawn Oakman under investigation for rape

Alex ButlerCHICAGO, April 7 (UPI) -- The man who many laughed at as the subject of a meme that shot to the top of the viral charts, is now the...

FDA targets arsenic in baby cereal

Agency moves to reduce harmful levels of contaminant in infant rice cereal

Canadian pharmacists seek 'front-line' role in dispensing medical marijuana

An association that represents individual pharmacists has changed its stance on medical cannabis, saying pharmacists should play a "front-line" role in dispensing the drug.

FDA OKs 'containment' bag for certain uterine surgeries

HealthDay News The FDA gave limited approval to PneumoLiner, a "tissue containment system," for use in conjunction with laparoscopic power morcellators in uterine surgery.

[Report] SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions

Tumor-derived extracellular vesicles (tEVs) are important signals in tumor–host cell communication, yet it remains unclear how endogenously produced tEVs affect the host in different areas of the body. We combined imaging and genetic...

[Report] Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio

A decline in electron transport chain (ETC) activity is associated with many human diseases. Although diminished mitochondrial adenosine triphosphate production is recognized as a source of pathology, the contribution of the associated reduction...

[Report] MYC regulates the antitumor immune response through CD47 and PD-L1

The MYC oncogene codes for a transcription factor that is overexpressed in many human cancers. Here we show that MYC regulates the expression of two immune checkpoint proteins on the tumor cell surface:...

[Special Issue Review] Hypoxic control of metastasis

Metastatic disease is the leading cause of cancer-related deaths and involves critical interactions between tumor cells and the microenvironment. Hypoxia is a potent microenvironmental factor promoting metastatic progression. Clinically, hypoxia...

[Perspective] How neutrophils promote metastasis

Metastatic disease is the main cause of death in cancer patients. Despite its devastating effects, the complex processes that lead to metastasis are poorly understood. During their journey to distant...

[Editorial] The transformation of oncology

When I was trained at a prominent New York medical center in the 1960s, cancer was relegated to a minor place in the curriculum. Cancer patients were housed in a...

[Errata] Erratum for the Report “MYC regulates the antitumor immune response through CD47 and PD-L1” by S. C. Casey, L. Tong, Y. Li, R. Do, S. Walz, K. N. Fitzgerald, A. M. Gouw, V. Baylot, I. Gütgemann, M. Eilers, D. W. Felsher

Nanoparticles show promise for treating intestinal inflammation, study finds

Nanoparticles designed to block a cell-surface molecule that plays a key role in inflammation could be a safe treatment for inflammatory bowel disease, according to researchers.

Security flaws found in three state health insurance websites

Federal investigators found significant cybersecurity weaknesses in the health insurance websites of California, Kentucky and Vermont that could enable hackers to get their hands on sensitive personal information about hundreds...

LAPD investigates Charlie Sheen over 'felony threat'

Marilyn MalaraLOS ANGELES, April 7 (UPI) -- Charlie Sheen is under investigation by the Los Angeles Police Department after recordings of the actor confessing to making harrowing threats were published...

LA LGBT Center's canvassing conversations reduce transphobia, study finds

Researchers from Stanford University and the University of California, Berkeley, report in today's edition of Science that volunteer canvassers - both transgender and not - reduced voters' prejudice against transgender...

FDA approves first wire-free pacemaker

HealthDay News The first leadless, wire-free heart pacemaker has been approved by the U.S. Food and Drug Administration.