This Fungus Is A Weapon Of Mass Destruction Against Antibiotic Resistance

Wednesday, June 25, 2014 - 18:30 in Biology & Nature

A fungus living in the soils of Nova Scotia may be a secret weapon in the battle against drug-resistant germs that kill tens of thousands of people every year, including one considered a serious global threat. A team of researchers has discovered a fungus-derived molecule known as AMA is able to disarm one of the most dangerous antibiotic-resistance genes: NDM-1 or New Delhi Metallo-beta-Lactamase-1, identified by the World Health Organization as a global public health threat.   Discovering the properties of the fungus-derived molecule is critical because it can provide a means to target and rapidly block the drug-resistant pathogens that render carbapenem antibiotics—a class of drugs similar to penicillin—ineffective. read more

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