Antibiotic 'Smart Bomb' Targets Specific Strains Of Bacteria

Thursday, January 30, 2014 - 12:31 in Biology & Nature

No more killing the good bacteria along with the bad. An antibiotic "smart bomb" can identify specific strains of bacteria and sever their DNA, eliminating the infection and reducing multi-drug resistant bacteria. The new approach works by taking advantage of a part of an immune system present in many bacteria called the CRISPR-Cas system. The CRISPR-Cas system protects bacteria from invaders such as viruses by creating small strands of RNA called CRISPR RNAs, which match DNA sequences specific to a given invader. When those CRISPR RNAs find a match, they unleash Cas proteins that cut the DNA. read more

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